Schizophrenia & Genes

Over the past decade genome-wide association studies (GWAS) have provided fundamental insights into the genetic architecture of schizophrenia, having identified more than 100 risk loci and shown that both common and rare variants contribute to a  complex genetic predisposition to disease. However, these ground-breaking discoveries have come with the realization that the identification of risk loci is only the beginning of a long road toward meaningful biological understanding of  disease.